MOLECULAR CLONING AND EXPRESSION OF THE LEISHMANIA TROPICA KMP-11 GENE
نویسندگان
چکیده
منابع مشابه
molecular cloning and expression of the leishmania infantum kmp-11 gene
conclusions the results of the present study will increase our knowledge about molecular cloning and expression of the l. infantum kmp-11 gene, and this may be used as an effective target for controlling visceral leishmaniasis. results the kmp-11 gene was successfully subcloned in pcdna3 as a eukaryotic expression vector. recombinant kmp-11 protein was confirmed by the reverse transcriptase pol...
متن کاملMolecular Cloning and Expression of the Leishmania infantum KMP-11 Gene
Background: Visceral leishmaniasis (Kala-azar) is one of the most serious tropical diseases, and it can lead to death. The kinetoplastid membrane protein-11 (KMP-11) is highly conserved in all stages of the Leishmania life cycle. Objectives: In the present study, the KMP-11 gene was extracted from Leishmania infantum and then, cloned and expressed in an expression vector.The main objective of t...
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BACKGROUND Leishmania Homologue of receptors for Activated C Kinase (LACK) antigen is a 36-kDa protein, which provokes a very early immune response against Leishmania infection. There are several reports on the expression of LACK through different life-cycle stages of genus Leishmania, but only a few of them have focused on L.tropica. METHODS The present study provides details of the cloning,...
متن کاملsequencing and gene expression analysis of leishmania tropica lack gene.
background: leishmania homologue of receptors for activated c kinase(lack) antigen is a 36-kda protein, which provokes a very early immune response against leishmania infection. there are several reports on the expression of lack through different life-cycle stages of genus leishmania , but only a few of them have focused on l.tropica . methods: the present study provides details of the cloning...
متن کاملCLONING AND EXPRESSION OF LEISHMANOLYSIN GENE FROM LEISHMANIA MAJOR IN PRIMATE CELL LINES
Leishmanolysin is a worldwide disease that is caused by different species of the genus Leishmania. Leishmanolysin, One of the genes expressed by Leishmania, appears to be an ideal candidate for genetic vaccination. In this study, a full length sequence, which encodes Leishmanolysin functionally critical regions (amino acids 100-579), was cloned from a Leishmania strain endemic to Iran. Analysis...
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ژورنال
عنوان ژورنال: Journal of the Egyptian Society of Parasitology
سال: 2014
ISSN: 2090-2549
DOI: 10.21608/jesp.2014.90383